The purpose of this biobehavioral pain research program announcement (PA) is
to inform the scientific community of the interests of the various institutes
at the National Institutes of Health (NIH) and to stimulate and foster a wide
range of basic and clinical studies on pain as they relate to the missions of
these Institutes.
Applications are encouraged to study individual differences in pain responses
that may be due to factors such as genetic differences, endocrine activity,
neural activity, immune function, psychological state, developmental stage,
cognitive capacity, disability state, age, gender, social context and cultural
background. The pain experience needs to be examined at all levels of research
including the gene, molecule, cell, organ, and individual with the goal of
developing biobehavioral interventions to manage or prevent pain.
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Expiration Date: Sunday, July 30, 2006 NOFO Number: PA-03-152 Release Date: Friday, July 11, 2003 Notice Type: PA
Expiration Date: Friday, November 14, 2003 NOFO Number: RFA-HL-04-001 Release Date: Wednesday, July 2, 2003 Notice Type: RFA
This RFA provides support for the establishment of a Resuscitation
Research Consortium to conduct clinical research in the areas of
cardiopulmonary arrest and traumatic injury leading to arrest. This
Clinical Research Consortium (the Consortium), consisting of up to
seven Regional Clinical Centers (RCCs) and a Data and Coordinating
Center (DCC), will provide the necessary infrastructure to conduct
multiple collaborative trials to aid rapid translation of promising
scientific and clinical advances to improve resuscitation outcomes.
Trials may evaluate existing or new therapies (such as pharmacologic
interventions, strategies of fluid resuscitation, and the use of
immunomodulators), defined or proposed clinical management strategies
(such as bleeding control strategies, the use of cerebral protection
and neurologic preservation, metabolically directed therapies, and
alternative CPR approaches), or a combination of the two.
For the purpose of this document, cardiopulmonary arrest is defined as
primary cardiopulmonary collapse. Traumatic arrest is defined as trauma
leading to or threatening cardiopulmonary collapse. Resuscitation
research is defined as the field of investigation that attempts to
provide the best and most effective treatment for arrest patients.
Expiration Date: Friday, November 14, 2003 NOFO Number: RFA-DK-03-015 Release Date: Thursday, June 26, 2003 Notice Type: RFA
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK),
National Institute of Allergy and Infectious Diseases (NIAID), National Eye
Institute (NEI), National Heart, Lung, and Blood Institute (NHLBI), National
Institute of Neurological Disorders and Stroke (NINDS), National Institute of
Nursing Research (NINR), and the Office of Dietary Supplements (ODS) invite
applications to support collaborations between investigators who focus their
research efforts on type 1 diabetes or its complications and researchers from
other research areas with expertise relevant to type 1 diabetes research. The
purpose of this Request for Applications (RFA) is to attract new research
talent to type 1 diabetes research, strengthen the ongoing efforts of type 1
diabetes researchers by providing access to specialized expertise or
technologies relevant to their research, and facilitate the formation of
interdisciplinary research partnerships to investigate significant biological
and medical problems associated with type 1 diabetes. Applications should
propose collaborative research partnerships between independent principal
investigators, at least one currently pursuing research relevant to type 1
diabetes and one (or more) with expertise relevant to some aspect of type 1
diabetes that is not currently being applied by the investigator to research
on this disease. This RFA encourages type 1 diabetes researchers to act as
"talent scouts" by identifying and recruiting leading scientists with
relevant scientific expertise to the field of type 1 diabetes research. A
similar RFA (DK-02-023) was issued in 2002. We anticipate that a future
solicitation will provide an opportunity for expanded support for successful
collaborations funded through the current RFA.
Expiration Date: Monday, August 2, 2004 NOFO Number: PAR-03-134 Release Date: Wednesday, June 4, 2003 Notice Type: PAR
Over the past nine years the NSF, the NIH, and other federal agencies, have
supported the development of network-based virtual laboratories, following
the recommendations of the 1993 National Research Council (NRC) report
National Collaboratories: Applying Information Technology for Scientific
Research. As described in the NRC report, collaboratories are expected to
improve the speed and output of scientific research through Internet access
to instruments, data, and colleagues independent of time and place. Many
of the early collaboratory projects focused on remote control of distant
equipment with less emphasis on data. Changes since 1993 in both the
character of biomedical and chemical research, and in underlying computer and
network technologies suggest a re-examination of the collaboratory concept
with increased attention to data flow from acquisition to deposition in a
data repository, data reuse after deposition, and integration of data across
various repositories and databases. The purpose of this program announcement
(PA) is to invite proposals to develop tools and techniques to harness the
unprecedented volume of data generated by collaborations among researchers.
Proposals dealing with data from either research laboratories or from the
clinical laboratories are welcome. Using these new tools and techniques, it
is expected that two or more laboratories will be able to productively
collaborate in ways that are not currently possible.
Expiration Date: Saturday, September 30, 2006 NOFO Number: PAS-03-131 Release Date: Monday, June 2, 2003 Notice Type: PAS
This is a program announcement (PA) with set-aside funds. The PA is
designed to stimulate and support research on sleep disorders in
Parkinson's disease (PD) and Parkinson's related neurological conditions
(PRNC). Support will be for research on PD and PRNC patients as well as
patients in appropriate comparison groups and/or healthy control subjects.
Responsive applications could deal with the following areas: natural
history of symptoms studies, mechanistic studies of the sleep disturbances
in PD and PRNC, associated sleep disorders such as Restless Legs Syndrome
(RLS) and sleep-disordered breathing (SDB), and studies of the sleep-
related effects of pharmacotherapies for PD and PRNC. The timing and scope
of this PA are predicated on recent research and clinical findings
indicating promising new directions for the diagnosis and care of patients
with PD and PRNC.
Expiration Date: Saturday, November 15, 2003 NOFO Number: RFA-NS-04-001 Release Date: Friday, May 30, 2003 Notice Type: RFA
The Office of Research Integrity (ORI, DHHS), the National Institute of
Neurological Disorders and Stroke (NINDS, NIH), the National Institute
of Nursing Research (NINR, NIH), the National Institute on Drug Abuse
(NIDA, NIH), and the Agency for Healthcare Research and Quality (AHRQ,
DHHS) invite applications to support research on research integrity.
The purpose of the proposed grant program is to foster empirical
research on societal, organizational, group, and individual factors
that affect, both positively and negatively, integrity in research.
Proposals must have clear relevance to biomedical, behavioral and
health services research. Applicants are strongly encouraged to take
into consideration problems or issues that are relevant to the missions
of DHHS, NIH, or specific NIH institutes and programs.
For the purposes of this RFA, "research" is interpreted broadly to
include societal, organizational, group, and individual aspects of the
enterprise. "Integrity" is understood as "the use of honest and
verifiable methods in proposing, performing, and evaluating research in
reporting research results with particular attention to adherence to
rules, regulations, guidelines, and commonly accepted professional
codes or norms."
Expiration Date: Saturday, July 12, 2003 NOFO Number: RFA-OD-03-007 Release Date: Thursday, May 22, 2003 Notice Type: RFA
The purpose of this initiative is to provide short-term interim support for
institutional activities that will strengthen oversight of human subjects
research at institutions that receive significant NIH support for clinical
research. While there is considerable flexibility in the types of activities
that could be supported under this program, it is important that these
enhance the protection of research subjects by means that will be sustained
by the institution after the award period ends. This is a limited
solicitation made available to the grantees funded under the first
RFA (OD-02-003) as a recompetition for an additional, final, one-year award.
HOWEVER, FOR THIS SOLICITATION, THE NIH REQUIRES APPLICANTS TO COLLABORATE
WITH OTHER INSTITUTIONS CONDUCTING HUMAN SUBJECTS RESEARCH AND ARE NOT
CURRENTLY FUNDED UNDER THIS PROGRAM, TO SHARE EDUCATIONAL RESOURCES, COMPUTER
TECHNOLOGIES, BEST PRACTICES, ETC. While all NIH components supporting
clinical research are providing support for this program, it will be
administered by the National Center for Research Resources.
Expiration Date: Thursday, September 22, 2005 NOFO Number: PAR-03-118 Release Date: Friday, May 16, 2003 Notice Type: PAR
This Program Announcement (PA) is intended to promote productive re-entry of
NIH-trained foreign investigators from low-income countries into their home
countries as part of a broader program to enhance the scientific research
infrastructure in developing countries, to stimulate research on a wide variety
of high priority health-related issues in these countries, and to advance NIH
efforts to address health issues of global import. The specific goal of this
initiative is to provide funding opportunities for the increasing pool of
foreign biomedical and behavioral scientists, clinical investigators, nurses,
and other health professionals with state-of-the-art knowledge of research
methods to advance critical issues in global health upon their return to their
home countries. After their term of research training, developing country
participants supported by this PA are expected to continue independent and
productive scientific careers, including expert training and consultation and/or
research of biomedical issues within their home institutions.
Expiration Date: Saturday, April 30, 2005 NOFO Number: PAS-03-120 Release Date: Monday, May 12, 2003 Notice Type: PAS
The National Institute of Neurological Disorders and Stroke (NINDS) invites
applications for research programs designed to advance our understanding of
the neurobiological mechanisms and epidemiology of Complex Regional Pain
Syndrome (CRPS)/Reflex Sympathetic Dystrophy (RSD). A major goal of this
initiative is to facilitate the development of novel collaborative research
programs among physiologists, neuroscientists, behavioral neuroscientists,
imaging specialists and clinicians in order to develop integrative research
programs to accelerate progress in CRPS/RSD research. This PA is intended to
encourage cross-disciplinary research focused on a mechanism-based diagnostic
classification of CRPS/RSD, which might lead to mechanism-based therapeutic
strategy for this chronic condition.
Expiration Date: Monday, December 19, 2005 NOFO Number: PAR-03-119 Release Date: Monday, May 12, 2003 Notice Type: PAR
Participating Institutes and Centers of the National Institutes of Health
(NIH) invite applications for innovative research in biomedical computational
science and technology to promote the progress of biomedical research.
There exists an expanding need to speed the progress of biomedical research
through the power of computing to manage and analyze data and to model
biological processes. The NIH is interested in promoting research and
developments in biomedical computational science and technology that will
support rapid progress in areas of scientific opportunity in biomedical
research. As defined here biomedical computing or biomedical information
science and technology includes, database design, graphical interfaces,
querying approaches, data retrieval, data visualization and manipulation,
data integration through the development of integrated analytical tools, and
tools for electronic collaboration, as well as computational research
including the development of structural, functional, integrative, and
analytical models and simulations.
This PA will utilize the Small Business Innovation Research (SBIR) and Small
Business Technology Transfer (STTR) mechanisms, but will be run in parallel
with a program announcement of identical scientific scope (PAR-03-106) that
will utilize the traditional research project grant (R01) or the phased
innovation award (R21/R33).