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This Funding Opportunity Announcement (FOA) encourages grant applications proposing the conduct of innovative, collaborative research and research training projects, between High Income country (HIC) and low- to middle-income country (LMIC) scientists, on nervous system function and disorders throughout life, relevant to LMICs. The collaborative research programs are expected to contribute to the long-term goals of building sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, treatment and prevention strategies.

This FOA solicits Research Program Project Grant (P20) applications from institutions/organizations proposing exploratory collaborative research on sudden unexpected death in epilepsy (SUDEP). This FOA is for support of new projects, not continuation of projects that have already been initiated. Successful exploratory studies may lead to future applications for support of a collaborative, multidisciplinary SUDEP Center without Walls.

The National Institute of Mental Health (NIMH), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Drug Abuse (NIDA), and the National Institute of Neurological Disorders and Stroke (NINDS) invite research grant applications focused on defining the pathogenic mechanisms involved in Human Immunodeficiency Virus (HIV)-1 Associated Neurocognitive Disorders (HAND) and identifying therapeutic strategies to treat and prevent the neurobehavioral and neurological effects of HIV-1 on the central nervous system (CNS). Applications ranging from basic research to clinical diagnosis and treatment in domestic and international settings are of interest. Multidisciplinary research teams and collaborative alliances are encouraged but not required.

The purpose of the FOA is to invite applications for Diversity Research Education grants whose goals are to support the development and/or implementation of programs to: (1) increase the number of Ph.D.-level research scientists from diverse backgrounds including graduate, post-doctoral and/or junior-faculty career levels; and (2) advance the careers of the participants to the next step in their education. Funding support for the R25 Diversity Research Education Programs should lead to increased recruitment, mentoring, education and retention of researchers from diverse backgrounds in the neuroscience scientific workforce.

Purpose: This FOA is an initiative of the NIH Blueprint for Neuroscience Research (http://neuroscienceblueprint.nih.gov), a trans-NIH partnership to accelerate neuroscience research. Sixteen Institutes and Centers (ICs) are participating in the Blueprint. This funding opportunity will enable the development of novel, interdisciplinary training programs that integrate comprehensive training in basic neuroscience, the physical and biological bases of neuroimaging, the technologies of in vivo neuroimaging, and the application of these technologies to understanding questions in neuroscience across the life span. Each training program must have two components: a] a pre-doctoral NRSA institutional training program (T90) and b] a short-term research education program (R90) that may include scientists at any stage of the career continuum who are interested in neuroimaging. Programs may also include a full-time non-NRSA institutional pre-doctoral training component (R90).. An external advisory committee, a dissemination plan, and an evaluation plan are required. Mechanism of Support: This funding opportunity will use the T90/R90 mechanism that includes linked research training and research education programs. Applicants will submit a single, unified grant application and, if selected for funding, two separate awards will be issued, a T90 (research training award) and a R90 (research education award) based on distinct research training and research education-related funding authorities. Funds Available and Anticipated Number of Awards: The participating Institutes have committed approximately $1.3M to support this FOA in FY11. However, the total amount awarded and the number of awards made will depend upon the number, quality, and cost of the applications received.

Purpose. This Funding Opportunity Announcement (FOA) is designed to promote research on tumor microenvironment with the focus on understanding the role of host stroma in tumorigenesis and responses to treatment. Through this FOA, the National Cancer Institute (NCI) and National Institute of Neurological Disorders and Stroke (NINDS) invite cooperative agreement applications from groups of investigators interested in forming Research Centers serving as components of an interactive NCI Tumor Microenvironment Network (TMEN). The main scientific objectives of TMEN are: 1) to generate a comprehensive understanding of composition of the stroma in normal tissues as well as its roles in tumor initiation, progression, and metastasis; 2) to delineate mechanisms of tumor-stroma interactions in human cancer; and 3) to identify the mechanism(s) by which tumor stroma may affect responses to treatment. In addition to these general NCI priorities, NINDS is particularly interested in research programs relevant to primary brain tumors or peripheral nervous system tumors. TMEN members will be expected to participate in collaborative efforts (to be developed within TMEN) that are directed at: 1) developing resources and reagents critical to the analysis of the tumor microenvironment; 2) developing novel technologies for use in tumor microenvironment research; and 3) outreach activities to facilitate dissemination of such resources and technologies to the broader research community. TMEN infrastructure is expected to establish repositories of critical reagents, resources, and information as well as promote and facilitate interdisciplinary collaborations both within and outside the Network. Mechanism of Support. This FOA will utilize the U54 cooperative agreement mechanism.

Purpose: This Funding Opportunity Announcement (FOA) is an initiative of the NIH Blueprint for Neuroscience Research (http://neuroscienceblueprint.nih.gov), a trans-NIH partnership to accelerate neuroscience research. Sixteen Institutes and Centers (ICs) are participating in the Neuroscience Blueprint. Awards will be administered by the National Institute on Drug Abuse (NIDA) on behalf of the Neuroscience Blueprint. This FOA will support integrated research education and research training programs that provide interdisciplinary training in basic neuroscience and the theoretical and technological approaches of computational neuroscience. Mechanism of Support: This FOA will use the T90 mechanism that includes linked research education and research training programs. Applicants will submit a single unified grant application and if selected for funding, two separate awards will be issued, an R90-research education award and a T90-research training award, based on distinct research education and research training-related funding authorities. Each application:

The NINDS intends to fund a multi-site, multi-project network (Parkinsons Disease Biomarker Identification Network, or PD-BIN) devoted to identifying biological markers for PD risk, onset, and/or progression, in order to facilitate development of disease-modifying treatments. The purpose of this FOA is to solicit linked cooperative agreement (U01) applications for the establishment of a Clinical Coordinating Center (CCC) and a Data Coordinating Center (DCC). The PIs for the DCC and CCC must coordinate their submissions. The CCC will be responsible for the oversight of all aspects of subject recruitment and specimen acquisition, including the management of multiple clinical sites (to be identified by the CCC applicant), enrollment of a core cohort of newly diagnosed patients with PD and matched controls, and accurate collection of all clinical and biological data. The DCC will provide all data management aspects for standardized acquisition, quality control, dissemination and public accessibility. The CCC and DCC must be flexible enough to accommodate and support a wide range of future add-on research projects seeking to utilize and augment the core PD-BIN data. Individual hypothesis-driven studies are not a component of this FOA. It is anticipated that all data and biospecimens acquired will be used to create a publicly available resource for biomarker validation and discovery. The CCC and the DCC will be expected to advance the general scientific goal of identifying and validating useful PD biomarkers.

Purpose. This Funding Opportunity Announcement (FOA) issued by the Fogarty International Institute (FIC), the National Cancer Institute (NCI), the National Institute on Aging (NIA), the National Institute of Environmental Health Sciences (NIEHS), the Office of Dietary Supplements, Office of the Director (ODS), the National Eye Institute (NEI), the National Institute of Mental Health (NIMH), the National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) encourages Research Project Grant (R01) applications from institutions/organizations that propose to conduct basic biomedical research relevant to global health. This program is intended to promote productive development of foreign investigators from low- and middle-income countries (LMICs), trained in the U.S. or in their home countries through an eligible NIH funded research or research training grant/award. It is expected that this program will stimulate research on a wide variety of high priority health-related issues in those countries, and advance NIH efforts to address important global health issues. Mechanism of Support. This FOA will utilize the NIH Research Project (R01) grant mechanism. Funds Available and Anticipated Number of Awards. The total amount to be awarded is $325,000 and the anticipated number of awards is six. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award may also vary. The total amount to be awarded and the number of awards will depend upon the quality and costs of the applications received.

The National Institutes of Health (NIH), Defense Advanced Research Projects Agency (DARPA), National Science Foundation (NSF), United States Department of Agriculture (USDA) and the Department of Homeland Security encourage applications for the development of technologies that will advance the field of robotics. Scientific interests for this joint-agency FOA include, but are not limited to, research directed towards innovations or advancements in robotic technologies and devices for: Robotics for Home Healthcare, Personalized Care for Special-needs Populations, and Robotic Wellness/Health Promotion; Robot-Assisted Recovery, Rehabilitation, and Behavioral Therapy; High-throughput Robotics Technologies; Better Than Biology Actuators; Patient Mobility and Rehabilitation Robotics; Dexterous Manipulators with Tactile Feedback; Multi-Agent Command, Coordination, and Communication; Robotic Co-Worker Assistive Technologies; robotics to render improvised explosive devices safe; and robotics for cross border tunnels. Specific areas of interests under this FOA are described under the Research Objectives.