The National Institute of Allergy and Infectious Diseases (NIAID),
National Institute of Neurological Disorders and Stroke (NINDS) and
National Institute of Arthritis and Musculoskeletal and Skin Diseases
(NIAMS) invite applications for basic and preclinical studies to
increase knowledge of the role of microbes in the development and
regulation of chronic pathologic immune responses, including
autoimmune diseases, and to identify the genetic factors that
increase or decrease the susceptibility to pathogen-induced immune
disease. Exploitation of animal models of microbe-induced autoimmune
disease to molecularly dissect the etiology and pathogenesis of
autoimmune disease would be relevant. The knowledge developed
through research into the mechanisms by which microbes break
tolerance to self antigens should provide information about the
underlying basis of autoimmunity.
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Expiration Date: Monday, May 10, 1999 NOFO Number: PA-96-051 Release Date: Friday, May 10, 1996 Notice Type: PA
Expiration Date: Monday, May 10, 1999 NOFO Number: PA-96-053 Release Date: Friday, May 10, 1996 Notice Type: PA
The National Institute of Allergy and Infectious Diseases (NIAID),
National Institute of Neurological Disorders and Stroke (NINDS),
National Institute of Diabetes, Digestive and Kidney Diseases
(NIDDK), National Institute of Arthritis and Musculoskeletal and Skin
Diseases (NIAMS), National Institute of Dental Research (NIDR), and
the Office of Research on Women"s Health (ORWH) invite applications
for basic studies that will increase knowledge of the mechanisms by
which gender influences the development of autoimmune disease and the
regulation of the immune response in individuals with these diseases.
Although it is clear that autoimmune diseases disproportionately
affect women, the reasons for this are not clear. Research into the
basic mechanisms by which sex hormones or non-hormonal gender
differences affect the immune response and protect from or contribute
to a break in self tolerance should allow for the development of
improved therapeutic and preventive strategies for autoimmune
disease.
Expiration Date: Monday, May 3, 1999 NOFO Number: PA-96-050 Release Date: Friday, May 3, 1996 Notice Type: PA
In response to new basic and clinical developments in Parkinson"s
disease research and the interest of related voluntary organizations,
the Senate Appropriations Subcommittee on Health in 1995 asked the
National Institute of Neurological Disorders and Stroke (NINDS) to
organize a conference to assess the progress made in Parkinson"s
disease research, to identify new opportunities and goals, and to
plan a research agenda to coordinate and strengthen the cooperative
activities of the several NIH institutes supporting research relevant
to this disorder. This meeting was held in August 1995 and, with
NINDS, was jointly sponsored by the National Institute on Aging, the
National Institute of Environmental Health Sciences, and the National
Institute of Mental Health. For fiscal year 1996 the Senate
Appropriations Committee urged the NINDS to expand its initiatives in
areas of promise identified at the August Parkinson"s research
conference. This Program Announcement (PA) is one of several
responses to Congressional interest in this subject.
Expiration Date: Tuesday, October 6, 1998 NOFO Number: PA-96-002 Release Date: Friday, October 6, 1995 Notice Type: PA
This Program Announcement (PA) replaces PA-93-068. The purpose of
this initiative is to encourage and support investigator-initiated,
neuroinformatics research that will lead to new digital tools for all
domains of brain and behavioral research. The advanced information
technologies resulting from this research are expected to be put to
wide use by the brain and behavioral science community. Therefore,
the approaches and technologies studied under the Human Brain Project
will be generalizable, scalable, and extensible, and will use
sophisticated, powerful computational resources.
Expiration Date: Tuesday, April 28, 1998 NOFO Number: PA-95-049 Release Date: Friday, April 28, 1995 Notice Type: PA
The Mentored Research Scientist Development Award (MRSDA) is for
research scientists who need an additional period of sponsored
research experience as a way to gain expertise in a research area new
to the candidate or in an area that would demonstrably enhance the
candidate's scientific career. It is expected that following this
experience, the candidate will be able to pursue an independent and
productive research career.
Expiration Date: Tuesday, April 28, 1998 NOFO Number: PA-95-053 Release Date: Friday, April 28, 1995 Notice Type: PA
The purpose of the Mentored Clinical Scientist Development Award
MCSDA is to support the development of outstanding clinician research
scientists. This mechanism provides specialized study for clinically
trained professionals who are committed to a career in research and
have the potential to develop into independent investigators. The
award supports a three, four, or five year period of supervised
research experience that may integrate didactic studies with
laboratory or clinically-based research. The proposed research
should have both intrinsic research importance and be a suitable
vehicle for learning the methodology, theories, and
conceptualizations necessary for a well trained independent
researcher.
Expiration Date: Wednesday, June 28, 1995 NOFO Number: RFA-MH-95-003 Release Date: Friday, April 28, 1995 Notice Type: RFA
The Office on AIDS, National Institute of Mental Health (NIMH),
supports investigations directed at developing effective strategies
to prevent or reduce behaviors that place individuals at risk for HIV
infection and fosters research to enhance the understanding of the
profound impact of the Human Immunodeficiency Virus (HIV) infection
on the central nervous system (CNS). In addition, the National
Institute of Neurological Disorders and Stroke (NINDS) supports
research on neurological aspects of HIV infection (neuro-AIDS) in
adults and children.
Expiration Date: Tuesday, April 28, 1998 NOFO Number: PA-95-056 Release Date: Friday, April 28, 1995 Notice Type: PA
The purpose of this biobehavioral pain research program announcement
is to inform the scientific community of the interests of the various
institutes at the National Institutes of Health (NIH) and to
stimulate and foster a wide range of basic and clinical studies on
pain as they relate to the missions of these Institutes.
Applications are encouraged to study individual differences in pain
responses which may be due to factors such as genetic differences,
endocrine activity, neural activity, immune function, psychological
state, disability state, age, gender, and cultural background.
Research is also needed in areas such as understanding the
neuroanatomical pathways and the neurophysiological mechanisms in
pain. The pain experience needs to be examined at all levels of
research including the gene, molecule, cell, organ, and individual
with the goal of developing biobehavioral interventions to manage or
prevent pain.
Expiration Date: Tuesday, April 14, 1998 NOFO Number: PAR-95-047 Release Date: Friday, April 14, 1995 Notice Type: PAR
The Division of AIDS (DAIDS), National Institute of Allergy and
Infectious Diseases (NIAID), solicits applications on the discovery,
preclinical efficacy evaluation, and development of novel agents and
strategies that suppress HIV replication, interfere with disease
progression, and ameliorate the consequences of infection.
Responsive applications will involve creative and original research
that emphasizes under- exploited facets of HIV infection. The
National Institute of Mental Health (NIMH) solicits grant
applications directed toward identifying the mechanisms underlying
the cognitive and behavioral changes associated with HIV infection.
The National Institute of Neurological Disorders and Stroke (NINDS)
solicits grant applications directed toward studies on the
neurological complications of HIV infection. Both institutes seek
grant applications investigating potential CNS-targeted drug
therapies that prevent or alleviate CNS dysfunction. Under this PA,
applications in the following areas are not being solicited: (1)
anti-viral agents and therapeutic strategies currently under intense
investigation, (2) clinical studies, (3) studies of AIDS- related
malignancies, and (4) studies of AIDS-associated opportunistic
pathogens. Support under this PA will be provided to inter-related
research consortia that include the private sector as one of its
Group components. Applications funded in response to this PA will
become part of the NCDDG-HIV.
Expiration Date: Tuesday, January 13, 1998 NOFO Number: PA-95-017 Release Date: Friday, January 13, 1995 Notice Type: PA
The National Institute of Neurological Disorders and Stroke (NINDS)
and the National Center for Medical Rehabilitative Research (NCMRR)
of the National Institute of Child Health and Human Development
(NICHD) announce the issuance of a program announcement to notify the
scientific community of their interest in the submission of research
grant applications concerning syringomyelia.