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This funding opportunity announcement (FOA) from the National Cancer Institute (NCI), the National Institute of Environmental Health Sciences (NIEHS), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and the National Institute of Neurological Disorders and Stroke (NINDS) invites Small Business Innovation Research (SBIR) applications from small business concerns (SBCs) for the development and delivery of novel in vivo image acquisition or enhancement technologies and methods for biomedical imaging and image-guided interventions and therapy (applications may incorporate limited pilot or clinical feasibility evaluations using either pre-clinical models or clinical studies).

- The goal of this Initiative is to create a clinical research network of emergency medicine physicians, neurologists, and neurosurgeons who will work together to efficiently develop more and better treatments for patients with acute neurological disorders through execution of NINDS-sponsored clinical trials - Funding of the clinical sites (hubs) and funding of the statistical coordinating center will be through separate RFAs. The statistical center RFA will follow the clinical coordinating center RFA by 6-12 months.

The Fogarty International Center (FIC) invites applications for International Research Ethics Education and Curriculum Development awards to develop graduate level curricula and provide opportunities for developing country academics, researchers and health professionals in international research ethics related to performing research involving human subjects.  New applications focusing on research ethics education/training for Mexico, Central America, China, Brazil, Thailand, Vietnam, Nigeria, Russia and the countries of the former Soviet Union are especially encouraged. U.S. and foreign applicants can request up to four years of support for up to $250,000 total costs (direct and F and A) per year for comprehensive curriculum development and training programs. Developing country applicants can request up to two years of support to $25,000 total costs (direct and F and A) per year for program planning and curriculum development in preparation to apply for comprehensive research educational program support in the future.

The purpose of the Academic Research Enhancement Award (AREA) program is to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. These AREA grants create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH programs, to contribute to the Nation's biomedical and behavioral research effort.

This funding opportunity provides updated guidelines for National Institutes of Health (NIH) support of conferences and scientific meetings. Because the nature and scope of the proposed activities will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the number of applications, quality, duration, and costs of the applications received. This funding opportunity announcement (FOA) will use the NIH conference grant (R13) and conference cooperative agreement (U13) award mechanisms.

On February 26, 2004, Executive Order 13329 (http://a257.g.akamaitech.net/7/257/2422/14mar20010800/edocket.access.gp…) was signed by President George W. Bush requiring agencies with Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, to the extent permitted by law and in a manner consistent with the mission of the Department, to give high priority within the SBIR and STTR programs to manufacturing-related research and development (R&D).In response to this Executive Order, NIH is expanding its focus by encouraging eligible United States small business concerns to submit STTR Phase I, Phase II, and Fast-Track grant applications whose biomedical research is related to advanced processing, manufacturing processes, equipment and systems, and manufacturing workforce skills and protection.

- The purpose of this FOA is to invite applications by small businesses for the commercial development of technologies for high throughput data acquisition and analysis that could aid the research fields of basic behavioral science or neuroscience relevant to the mission of the National Institute of Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS).  - Only Small Business Innovation Research (SBIR) Phase I, Phase II, and Fast Track grant applications are solicited by this FOA. - This funding opportunity will be run in parallel with a funding opportunity of identical scientific scope, “HIGH THROUGHPUT TOOLS FOR BRAIN AND BEHAVIOR” (PA-06-024) that will utilize the Small Business Technology Transfer (STTR [R41/R42]) grant mechanism. - Budgets up to $ 200,000 total costs per year and time periods up to 2 years for Phase I may be requested. Budgets up to $ 450,000 total costs per year and up to 3 years may be requested for Phase II. - No funds have been specifically set aside for this program; the number of awards and the amount of funds provided for awards have not been predetermined. - Only United States SBCs are eligible to submit SBIR applications. A SBC is one that, on the date of award for both Phase I and Phase II funding agreements, meets ALL of the criteria as described in Section III. I.A. - Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. On an SBIR application, the Project Director/Principal Investigator (PD/PI) must have his/her primary employment (more than 50%) with the SBC at the time of award and for the duration of the project. - Applicant SBCs may submit more than one application, provided each application is scientifically distinct. - See Section IV.1 for application materials. The application instructions for this Funding Opportunity Announcement (FOA) are located at the following links: http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_SBIR_STTR_Ver2… (MS Word) http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_SBIR_STTR_Ver2… (PDF) - For general information on SF424 (R&R) Application and Electronic Submission, see the following Web sites: - SF424 (R&R) Application and Electronic Submission Information: http://grants.nih.gov/grants/funding/424/index.htm - General information on Electronic Submission of Grant Applications: http://era.nih.gov/ElectronicReceipt/ - Telecommunications for the hearing impaired is available at: TTY 301-451-0088.

On February 26, 2004, Executive Order 13329 (http://a257.g.akamaitech.net/7/257/2422/14mar20010800/edocket.access.gp…) was signed by President George W. Bush requiring SBIR/STTR agencies, to the extent permitted by law and in a manner consistent with the mission of the Department, to give high priority within the SBIR and STTR programs to manufacturing-related research and development (R&D).In response to this Executive Order, NIH is expanding its focus by encouraging eligible United States small business concerns to submit SBIR Phase I, Phase II, and Fast-Track grant applications whose biomedical research is related to advanced processing, manufacturing processes, equipment and systems, and manufacturing workforce skills and protection.

- This funding opportunity announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications that propose research and development of probes useful in imaging the structure and function of the brain and other parts of the nervous system, with award duration and amounts greater than those routinely allowed under the SBIR programs. Specifically this FOA solicits SBIR applications that propose research and development of probes that generate signals detectable by one or more imaging modality. Such probes should indicate the structure or function of molecules or subcellular elements of neurons or other cells of the nervous system. Of special interest are applications that propose research and development of novel probes, although significant enhancements of already existing probes are also solicited. Grant applications may propose projects that will result in probes solely intended for use in research or probes that might have clinical utility. It is expected that this initiative will require expertise from a variety of disciplines, including neuroscience, biology, chemistry, physics, engineering, biotechnology, and bioengineering. Moreover, it is anticipated that these types of expertise will be brought together in various combinations in individual proposed projects. - Budgets up to $200,000 total costs per year and time periods up to 2 years for Phase I may be requested. Budgets up to $400,000 total costs per year and up to 3 years may be requested for Phase II. - No funds have been specifically set aside for this program; the number of awards and the amount of funds provided for awards have not been predetermined. - This funding opportunity will be run in parallel with a funding opportunity of identical scientific scope, Probes for Microimaging The Nervous System (PA-06-022) that will utilize the Small Business Technology Transfer (STTR [R41/R42]) grant mechanisms. - Only United States SBCs are eligible to submit SBIR applications. A SBC is one that, on the date of award for both Phase I and Phase II funding agreements, meets ALL of the criteria as described in Section III. I.A. - Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. On an SBIR application, the Project Director/Principal Investigator (PD/PI) must have his/her primary employment (more than 50%) with the SBC at the time of award and for the duration of the project. - Applicant SBCs may submit more than one application, provided each application is scientifically distinct. - See Section IV.1 for application materials. The application instructions for this Funding Opportunity Announcement (FOA) are located at the following links: - http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_SBIR_STTR_Ver2… (MS Word) - http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_SBIR_STTR_Ver2… (PDF) - For general information on SF424 (R&R) Application and Electronic Submission, see the following Web sites: - SF424 (R&R) Application and Electronic Submission Information: http://grants.nih.gov/grants/funding/424/index.htm - General information on Electronic Submission of Grant Applications: http://era.nih.gov/ElectronicReceipt/ - Telecommunications for the hearing impaired is available at: TTY 301-451-0088

- The purpose of this FOA is to invite applications by small business concerns (SBC) for the commercial development of technologies for high throughput data acquisition and analysis that could aid the research fields of basic behavioral science or neuroscience relevant to the mission of the National Institute of Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS).  - Only STTR Phase I, Phase II, and Fast Track grant applications are solicited by this FOA. - This funding opportunity will be run in parallel with a funding opportunity of identical scientific scope, “HIGH THROUGHPUT TOOLS FOR BRAIN AND BEHAVIOR” (PA-06-023) that will utilize the Small Business Innovation Research (SBIR [R43/R44] grant mechanisms. - Budgets up to $200,000 total costs per year and time periods up to 2 years for Phase I may be requested. Budgets up to $450,000 total costs per year and up to 3 years may be requested for Phase II. - No funds have been specifically set aside for this program; the number of awards and the amount of funds provided for awards have not been predetermined. - Only United States SBCs are eligible to submit STTR applications. A SBC is one that, on the date of award for both Phase I and Phase II funding agreements, meets ALL of the criteria as described in Section III.I.A. - Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. On an STTR application, the Project Director/Principal Investigator (PD/PI) may be employed with the small business concern or the participating non-profit research institution as long as he/she has a formal appointment with or commitment to the applicant small business concern, which is characterized by an official relationship between the small business concern and that individual. - Applicant SBCs may submit more than one application, provided each application is scientifically distinct.·  - See Section IV for application materials. The application instructions for this Funding Opportunity Announcement (FOA) are located at the following links: http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_SBIR_STTR_Ver2… (MS Word) http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_SBIR_STTR_Ver2… (PDF) - For general information on SF424 (R&R) Application and Electronic Submission, see the following Web sites: SF424 (R&R) Application and Electronic Submission Information: http://grants.nih.gov/grants/funding/424/index.htm - General information on Electronic Submission of Grant Applications: http://era.nih.gov/ElectronicReceipt/ - Telecommunications for the hearing impaired is available at: TTY 301-451-0088