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This Funding Opportunity Announcement (FOA), issued as part of the NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet), encourages research grant applications that propose to increase understanding of the basic cognitive, affective, motivational, and social processes that underlie decision making across the lifespan.This includes an appreciation of the interactions among the psychological, neurobiological, and behavioral processes in decision making.It also includes consideration of the mediating and/or moderating influences of genetics, physiology, the social environment, and culture.

The purpose of this funding opportunity announcement (FOA) issued by NINDS is to solicit applications to support a national program of mentored advanced research career development for junior neurosurgeon faculty at institutions nationwide that support neurosurgical research. The goal of the program is to expand the cadre of neurosurgeon-researchers who will combine their clinical and research expertise to conduct research into neurological disorders that neurosurgeons are uniquely qualified to conduct.

This funding opportunity announcement (FOA) encourages research grant applications from institutions/organizations to develop novel, robust analytical platforms using in vitro assays to reveal changes in neuronal and/or glial function. The goal is to adapt state-of-the-art measures of basic cellular processes or molecular events that are key mediators of nervous system function with the intent to probe mechanisms and/or perturbations in an unbiased and efficient manner. The novel assay platforms would provide opportunities to measure neurobiological endpoints and build a pipeline to be used in the context of target identification and drug discovery.

This NIH Funding Opportunity Announcement (FOA), supported by funds from the NIH Common Fund (Common Fund) and participating NIH Institute(s) and Center(s), invites applications from foreign Institutions in African countries who wish to develop the study of genomic/genetic/environmental contributors of human health and disease within Africa, using cutting edge research tools to understand health and diseases affecting African populations more completely and increase capacity for biomedical research, in terms of building infrastructure (including data and research resources), genomic proficiency of researchers and numbers of trainees. In partnership with the Wellcome Trust, the H3Africa initiative is focused on supporting these efforts as part of an effort to promote sustainable research in Africa that will promote health and combat disease.

This NIH Funding Opportunity Announcement (FOA), supported by funds from the NIH Common Fund (Common Fund) and participating NIH Institute(s) and Center(s), invites applications from foreign Institutions in African countries who wish to develop the study of genomic/genetic/environmental contributors of human health and disease within Africa, using cutting edge research tools to understand health and diseases affecting African populations more completely and increase capacity for biomedical research, in terms of building infrastructure (including data and research resources), genomic proficiency of researchers and numbers of trainees. In partnership with the Wellcome Trust, the H3Africa initiative is focused on supporting these efforts as part of an effort to promote sustainable research in Africa that will promote health and combat disease.

This Funding Opportunity Announcement (FOA) solicits Research Program Project Grant (P20) applications from institutions/organizations proposing exploratory collaborative research on disease modification or prevention in an epilepsy syndrome. Successful exploratory studies may lead to subsequent applications for support of a collaborative, multidisciplinary Epilepsy Center without Walls on Disease Modification and Prevention. Depending on the topic area, however, exploratory studies may alternatively lead to applications for the NINDS Translational Program for Resistant Epilepsy and Epileptogenesis, the NINDS Clinical Trials Program, or additional investigator initiated research programs. This FOA is for support of new projects, not continuation of projects that have already been initiated. Interventional clinical trials are also not appropriate for this FOA.

This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) to address different and complementary research needs for the development appropriate pediatric drug formulations in different age groups. This FOA also encourages the development and testing of novel drug delivery systems in the pediatric population. The goal of this FOA is not to duplicate or compete with the private sector but to complement and accelerate the development of appropriate pediatric drugs formulations and drug delivery systems.

This Funding Opportunity Announcement (FOA) invites Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) to address different and complementary research needs for the development appropriate pediatric drug formulations in different age groups. This FOA also encourages the development and testing of novel drug delivery systems in the pediatric population. The goal of this FOA is not to duplicate or compete with the private sector but to complement and accelerate the development of appropriate pediatric drugs formulations and drug delivery systems.

The goal of this funding opportunity announcement (FOA) is to support preclinical development and testing of new therapies for neurological disorders. The program will facilitateencouragement, development, and review of therapy-directed projects to accelerate the translation of basic research discoveries into therapeutic candidates for clinical testing. To be eligible for support, projects must include therapeutic leads and in vivo proof of concept on efficacy. The program supports preclinical optimization and testing of the leads, and projects must be sufficiently advanced that an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application to the Food and Drug Administration (FDA) can be submitted by the end of the project period. The program does not support early-stage therapeutic discovery activities such as screening. The program also excludes clinical research, basic research, and studies of disease mechanism. The scope includes only therapy development activities, so development of diagnostics, biomarkers, or rehabilitation strategies cannot be supported. This is a milestone-driven cooperative agreement program involving participation of NINDS staff in the development of the project plan and monitoring of research progress.

The goal of this Funding Opportunity Announcement (FOA) is to support preliminary steps in the preclinical development of therapeutics for neurological disorders. Such projects, if successful, should lead directly to a subsequent project that will include all remaining activities for submission of an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application to the Food and Drug Administration (FDA). The scope includes only therapy development activities, so development of diagnostics, biomarkers, or rehabilitation strategies cannot be supported. Clinical research, basic research, and studies of disease mechanism are outside program scope.