Notice Additional Due Date Additional Areas Focus Especially Interest PAR-19-373 PAR-19-384, Research Biopsychosocial Factors Social Connectedness Isolation Health, Wellbeing, Illness, Recovery R01)" Notice Number: NOT-OD-20-103 Key Dates Release Date: 7, 2020 Related Announcements PAR-19-373 PAR-19-384 Issued NIH Basic Behavioral Social Science Opportunity Network OPPNET) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Drug Abuse NIDA) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Institute Minority Health Health Disparities NIMHD) National Center Complementary Integrative Health NCCIH) applications this funding opportunity announcement should fall within mission the Institutes/Centers. following NIH Offices co-fund applications assigned those Institutes/Centers. Office Behavioral Social Sciences Research OBSSR) Purpose purpose this Notice to add third due date additional areas focus especially interest PAR-19-373 PAR-19-384 Research Biopsychosocial Factors Social Connectedness Isolation Health, Wellbeing, Illness, Recovery R01 Clinical Trials Allowed/Basic Experimental Studies Humans Required), between two current due dates, March 17, 2020 March 17, 2021. Part 1 both PARs, under Key Dates, additional application due date June 8, 2020, added. I. Part 1 Key Dates PAR-19-373 PAR-19-384 Currently Reads: Application Due Date(s): March 17, 2020; March 17, 2021 applications due 5:00 PM local time applicant organization. types non-AIDS applications allowed this funding opportunity announcement due the listed date(s). Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. II. Part 1 Key Dates PAR-19-373 PAR-19-384 Modified this Notice) Read italics): Application Due Date(s): March 17, 2020; June 8, 2020; March 17, 2021 Scientific Merit Review: June 2020, October 2020, June 2021 applications due 5:00 PM local time applicant organization. types non-AIDS applications allowed this funding opportunity announcement due the listed date(s). Applicants encouraged apply early allow adequate time make any corrections errors found the application during submission process the due date. Scientific Merit Review: June 2020, October 2020; June 2021 Advisory Council Review: August 2020, January 2021, August 2021 III. Part 1 Key Dates PAR-19-373 PAR-19-384 Remain Unmodified: Earliest Start Date September 2020 Expiration Date March 18, 2021 Part 1 both PARs, under Part 2, Section I. Funding Opportunity Description, of Three areas focus especially interest OppNet participating NIH ICOs include, are limited to, those listed below appear as, 1. Effects social connectedness, connection, isolation across lifespan Affective cognitive function during aging process Contextual factors increase mitigate impact disruption isolation different developmental time points, e.g., Caregivers people dementia, severe illness, end-of-life Chronic illness limited mobility Perceived strength quality extant social connections Recent diagnosis a serious medical illness Sleep changes across lifespan e.g. during adolescence, early parenthood, menopause) Molecular markers mechanisms e.g., epigenetic modifications, gene expression, microbiome alterations, telomere attrition) associated changes social connectedness Neurobiological developmental trajectories Protective and/or risk factors associated isolation connection disruption different times development over lifespan e.g., adolescence, death mate/parent, middle-age males, onset serious medical diagnosis) Aggressive behaviors and/or risky sexual activity associated connection trajectories Mechanisms connectedness, connection, isolation Neurobiological factors Impact structure function the nervous system central, peripheral, autonomic) Impact neuroimmune neuroendocrine systems Impact neural systems associated basic affective, cognitive, social processes Importance inter-individual neural synchrony mediating moderating effects relationship trajectories Neurobiological biosignatures predict sensitivity connection disruption isolation Neurobiological processes could targets ameliorate negative effects disruption isolation Neurophysiological consequences disruption isolation substance disorders SUDs) mental illness Behavioral environmental factors consequences perceived isolation e.g., loneliness) and/or objective/observed isolation behavioral clinical outcomes adolescence adulthood Connections between social disruption/isolation specific populations and/or health/illness contexts, e.g., Sex/gender differences; sexual gender minorities Racial/ethnic differences, acculturation/bicultural adaptations contributions social integration versus isolation Autism, HIV, mental illness, recovery status, substance disorder Whether source connection disruption leads different processes outcomes E.g., Self-induced isolation versus isolation others, sense undesired loneliness vs. sought solitude Modified this Notice) Read italics): 1. Effects social connectedness, connection, isolation across lifespan Affective cognitive function during aging process Contextual factors increase mitigate impact disruption isolation different developmental time points, e.g., Caregivers people COVID-19, dementia, severe illness, end-of-life Chronic illness limited mobility Perceived strength quality extant social connections Recent diagnosis a serious medical illness including, not limited to, COVID-19 Sleep changes across lifespan e.g. during adolescence, early parenthood, menopause) Molecular markers mechanisms e.g., epigenetic modifications, gene expression, microbiome alterations, telomere attrition) associated changes social connectedness Neurobiological developmental trajectories Protective and/or risk factors associated isolation connection disruption different times development over lifespan e.g., adolescence, death mate/parent, middle-age males, onset serious medical diagnosis) Aggressive behaviors and/or risky sexual activity associated connection trajectories Mechanisms connectedness, connection, isolation Neurobiological factors Impact structure function the nervous system central, peripheral, autonomic) Impact neuroimmune neuroendocrine systems Impact neural systems associated basic affective, cognitive, social processes Importance inter-individual neural synchrony mediating moderating effects relationship trajectories Neurobiological biosignatures predict sensitivity connection disruption isolation Neurobiological processes could targets ameliorate negative effects disruption isolation Neurophysiological consequences disruption isolation substance disorders SUDs) mental illness Behavioral environmental factors consequences perceived isolation e.g., loneliness) and/or objective/observed isolation behavioral clinical outcomes adolescence adulthood Connections between social disruption/isolation specific populations and/or health/illness contexts, e.g., Sex/gender differences; sexual gender minorities Racial/ethnic differences, acculturation/bicultural adaptations contributions social integration versus isolation Autism, COVID-19, HIV, mental illness, recovery status, substance disorder Whether source connection disruption leads different processes outcomes E.g., Self-induced isolation versus isolation others, sense undesired loneliness vs. sought solitude E.g., Isolation the result preventing COVID-19 a household, preventing COVID-19 infection within household NOTE: other aspects these funding opportunity announcements PAR-19-373 PAR-19-384) remain unchanged. Inquiries Please direct inquiries to: William Elwood, PhD Office Behavioral Social Sciences Research OBSSR) Telephone: 301-402-0116 Email:
william.elwood@nih.gov