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Invasive surgical procedures provide the unique ability to record and stimulate neurons within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and resources available to implement complex experimental protocols and are rarely aggregated in a manner that addresses research questions with appropriate statistical power. Therefore, this RFA seeks applications to assemble diverse, integrated, multi-disciplinary teams that cross boundaries of interdisciplinary collaboration to overcome these fundamental barriers and to investigate high-impact questions in human neuroscience. Projects should maximize opportunities to conduct innovative in vivo neuroscience research made available by direct access to brain recording and stimulating from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and quantitative, mechanistic models where appropriate. Awardees will join a consortium work group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

Excellent mentorship and superior training are critical to the development of exceptional future scientists. To recognize the crucial role great mentors play in the development of future leaders in neuroscience, the National Institute of Neurological Disorders and Stroke (NINDS) created the Landis Award for Outstanding Mentorship. This award provides $100,000.00 (direct costs) to up to five (5) faculty members, who have demonstrated a dedication to outstanding mentorship and training, to help foster the research career development of additional students and post-doctorates. NINDS hopes that this tangible award will impress upon the scientific community as a whole, and faculty and institutional leaders in particular, the high value NINDS places on outstanding training and mentorship. Further, NINDS hopes that it encourages institutions to reward individuals not only for outstanding research accomplishments but also for their impact on the lives of others, and the future of neuroscience, through outstanding mentorship and training.

In April 2018, the National Institutes of Health (NIH) launched theHelping to End Addiction Long-termSMInitiative or HEAL InitiativeSM, an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis. As part of this initiative, the National Institute of Neurological Disorders and Stroke (NINDS), with other NIH Institutes and Centers (ICs) of the HEAL Initiative, intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications from interdisciplinary teams to elucidate the mechanisms of device-based pain relief. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The FOA is expected to be published in summer 2021 with an expected application due date in fall 2021. This FOA will utilize the RM1 activity code. Details of the planned FOA are provided below.

The purpose of this Notice is to alert the community that the National Institute of Neurological Disorders and Stroke (NINDS) plans to publish a Funding Opportunity Announcement (FOA) to solicit applications for Materials to Enhance Training in Experimental Rigor (METER), which will support the compilation and refinement of educational materials that will be incorporated into a new cutting-edge online resource that aims to promote awareness, understanding, and practice of fundamental principles of rigorous biomedical research for researchers and other scientists in various career stages and learning environments. These materials will enable acquisition of knowledge and skills to recognize and conduct rigorous experimental research. A companion FOA will solicit applications for Creating an Educational Nexus for Training in Experimental Rigor (CENTER) to build the final web-based platform and produce the digital elements (e.g. videos, graphics, and interactive components) of the online resource (see related Notice). It is expected that METER and CENTER awardees will work collaboratively to evaluate, improve, and disseminate the educational resource. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The FOA is expected to be published in Summer 2021 with an expected application due date in October 2021. This FOA will utilize the UE5 activity code. Details of the planned FOA are provided below.

The purpose of this notice is to inform potential applicants of an Informational Webinar on the Summer Research Education Experience Program (R25).

The purpose of this Notice is to alert the community that the National Institute of Neurological Disorders and Stroke (NINDS) plans to publish a Funding Opportunity Announcement (FOA) to solicit applications for Creating an Educational Nexus for Training in Experimental Rigor (CENTER), which will build, evaluate, and disseminate a user-friendly, harmonized, and openly accessible educational resource to promote awareness, understanding, and utilization of the principles of rigorous biomedical research. CENTER will provide comprehensive administrative oversight, expertise required to establish and maintain the educational platform, and infrastructure to create cutting-edge digital educational components (e.g. videos, interactive activities, relevant scientific examples). A companion FOA will solicit applications for Materials to Enhance Training in Experimental Rigor (METER) to support subject matter experts to develop content for the educational resource (see related Notice). It is expected that CENTER and METER awardees will work collaboratively to evaluate, improve, and disseminate the educational resource. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The FOA is expected to be published in Summer 2021 with an expected application due date in October 2021. This FOA will utilize the UC2 activity code. Details of the planned FOA are provided below.

Change of application types allowed for BRAIN Initiative: Team-Research BRAIN Circuit Programs TeamBCP, RFA-NS-19-002 (U19 Clinical Trial Required) and RFA-NS-19-003 (U19 Clinical Trial Not Allowed). Effective immediately, this Notice allows Type 2, renewal applications for the remaining receipt date on October 29, 2021 by 5:PM local time of the applicant organization. Acceptance of new Type 1 applications remains unchanged.

The purpose of this notice is to inform applicants of a correction to the Funding Period for the initial milestone-driven Planning Phase (UG3) in PAR-21-237 "NINDS Efficacy Clinical Trials (UG3/UH3 Clinical Trial Required)".

This webinar will take you through the process of putting together an application for the NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award for RFA-NS-21-012. The webinar will go through each part of the application, including eligibility, specific aims and research strategy, sponsor and co-sponsor information, letters of reference and support, and other documents. Participation in the webinar, although encouraged, is optional and is not required for application submission.

The National Center for Complementary and Integrative Health (NCCIH), the National Institute on Aging (NIA), and the National Institute for Neurological Disorders and Stroke (NINDS) are requesting information to guide a National Institutes of Health (NIH) effort, in partnership with the Foundation for the National Institutes of Health (FNIH) and the Rene Fleming Foundation, on Developing Evidence-Based Music Therapies for Brain Disorders of Aging. The project aims to develop, validate, and disseminate a toolkit for music-based intervention protocols that researchers will be encouraged to use in NIH-funded interventional studies.