Researchers from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.
Press Releases
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Monday, February 28, 2022
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Monday, January 24, 2022
Using an experimental drug, researchers were able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene.
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Thursday, January 20, 2022
SARS-CoV-2 was initially identified as a respiratory virus, but it can affect the entire body, including the nervous system.
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Thursday, December 9, 2021
In a small study, researchers funded by the National Institutes of Health captured more than 1,000 hours of brain recordings from patients with OCD in the clinic and at home.
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Wednesday, October 6, 2021
The NIH Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.
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Thursday, September 30, 2021
NIH study identifies possible target for certain neurodegenerative disorders
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Thursday, September 23, 2021
NIH study in mice demonstrates the importance of quickly addressing infection
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Wednesday, September 15, 2021
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Friday, September 10, 2021
Chronic lesions with inflamed rims, or “smoldering” plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.
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Wednesday, September 8, 2021
Researchers have identified a pathway common to several types of axonal peripheral neuropathies (APNs), including multiple forms of Charcot-Marie-Tooth (CMT) disease, and have identified a possible drug target that could help treat the disorder.