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NINDS and the National Cancer Institute (NCI) encourage grant applications for research on understanding and preventing brain tumor dispersal.  This announcement is supported by 2 funding mechanisms:  R01 and R21.

Many brain tumors are highly invasive and, therefore, extremely difficult to treat.  Cells from the primary tumor often invade surrounding brain tissues, so that removal of the main tumor mass is not enough to prevent recurrence.  The goal of this announcement is to promote studies that:  (1) identify the properties of brain tumor cells that cause them to migrate; (2) determine how interaction of tumor cells with normal brain elements affects migration; and (3) translate understanding of these parameters into interventions that target invading tumor cells.

Potential applicants should contact Dr. Jane Fountain, Program Director, Neural Environment Cluster, NINDS; telephone: 301-496-1431; email:  fountai@ninds.nih.gov.  For a more detailed description of this program announcement, visit http://grants.nih.gov/grants/guide/pa-files/PAS-08-048.html or http://grants.nih.gov/grants/guide/pa-files/PAS-08-049.html.